With Melvin Ingram being placed on injury reserve with a designation to return, Jahleel Addae making his season debut today brings some good news for the Chargers and the defensive unit.
Keenan Allen will be active today, after a groin issue kept him limited in practice all week.
Jerry Attaochu is also active today, which will help with the depth at linebacker now that Ingram is gone until at least week 11.
For the Bills, the biggest names inactive today will be Keith Rivers, Cyrus Kouandjio, and Cyril Richardson.
Robert Woods and Sammy Watkins are active today, after both missed some time in practice this week and a questionable status for today.
San Diego Chargers
Inactive: Ryan Mathews, Dontrelle Inman, Steve Williams, Ricardo Mathews, Ryan Carrethers, Melvin Ingram (IR)
Active: Keenan Allen, Jahleel Addae, Antonio Gates, Dwight Freeney, Jerry Attaochu, Brandon Flowers, Rich Ohrnberger, Johnnie Troutman, Chris Davis, Corey Liuget
Buffalo Bills
Inactive: Ross Cockrell, Bryce Brown, Keith Rivers, Randell Johnson, Cyrus Kouandjio, Cyril Richardson, Chris Gragg
Probable: Sammy Watkins, Robert Woods, Jonathan Meeks, Chris Williams, Lee Smith, Stefan Charles