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Inactives: San Diego Chargers at San Francisco 49ers

The San Diego Chargers will be without three of their best players when they take on the San Francisco 49ers, who will be without their best running back. Which team will be able to survive their injuries best?

Kirby Lee-USA TODAY Sports

Here we go...

No real surprise on the list of Chargers inactives, but that doesn't make them any less effective. The Chargers will have a hard time winning the field position battle without Keenan Allen, Ryan Mathews, and Mike Scifres.

The big news for the 49ers is that Frank Gore is active and starting and Carlos Hyde is inactive. Many were expecting a big game from Hyde against the Chargers.